Product Description
UNC13D Polyclonal Antibody | E-AB-64476 | Elabscience
Type: Polyclonal Antibody
Synonyms: UNC13D, FHL3, HLH3, HPLH3, Munc13-4
Application: WB
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Reserch Areas: Immunology
Background: This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder.
Concentration: 1 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant fusion protein of human UNC13D (NP_954712.1).
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification Method: Affinity purification
Dilution: WB 1:1000-1:2000
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 41 kDa/123 kDa/128 kDa
Molecular Weight(Observed): 123 kDa