Product Description
NR1H4 Polyclonal Antibody | E-AB-62327 | Elabscience
Type: Polyclonal Antibody
Synonyms: NR1H4, BAR, FXR, HRR-1, HRR1, PFIC5, RIP14
Application: WB
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Reserch Areas: Epigenetics and Nuclear Signaling, Metabolism, Signal Transduction
Background: This gene encodes a ligand-activated transcription factor that shares structural features in common with nuclear hormone receptor family members. This protein functions as a receptor for bile acids, and when bound to bile acids, binds to DNA and regulates the expression of genes involved in bile acid synthesis and transport. Alternatively spliced transcript variants encoding different isoforms have been described.
Concentration: 1 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant fusion protein of human NR1H4 (NP_001193908.1).
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 48 kDa/54 kDa/55 kDa
Molecular Weight(Observed): 59 kDa