Product Description
CBX3 Monoclonal Antibody | E-AB-22145 | Elabscience
Type: Monoclonal Antibody
Synonyms: CBX 3, CBX3, CBX3, Chromobox homolog 3 (HP1 gamma homolog, Drosophila), Chromobox homolog 3, Chromobox protein homolog 3, GAMMA, HECH, Heterochromatin like protein 1, Heterochromatin protein 1 homolog gamma, Heterochromatin protein HP1 gamma, HP1 gamma, HP1 gamma homolog, HP1Hs gamma, Modifier 2 protein
Application: WB, IHC-p
Reactivity: Human, Mouse, Rat
Host: Mouse
Isotype: IgG
Reserch Areas: Cancer, Epigenetics and Nuclear Signaling
Background: At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks.
Concentration: 1 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant Protein of HP-1γ
Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Purification Method: Protein A purification
Dilution: WB 1:500-2000, IHC 1:50-300
Clone: Clone:6A4
Conjugation: Unconjugated
Molecular Weight(Calculated): N/A
Molecular Weight(Observed): 24 kDa