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Product Description
EIF4A1 Monoclonal Antibody | E-AB-22076 | Elabscience
Type: Monoclonal Antibody
Synonyms: ATP-dependent RNA helicase eIF4A-1, DDX2, DDX2A, eIF 4A I, eIF-4A-I, EIF4A, eIF4A I, eIF4A-I, EIF4A1, Eukaryotic initiation factor 4A-I, Eukaryotic initiation factor 4AI, eukaryotic translation initiation factor 4A, isoform 1, Eukaryotic translation initiation factor 4A1, IF4A1
Application: WB, IHC-p, IF
Reactivity: Human, Mouse, Rat
Host: Mouse
Isotype: IgG
Reserch Areas: Cancer, Epigenetics and Nuclear Signaling
Background: EIF4A1 is an ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.
Concentration: 1 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Synthetic Peptide
Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Purification Method: Protein A purification
Dilution: WB 1:500-1:3000, IHC 1:50-1:300, IF 1:100-1:200
Clone: Clone:2B6
Conjugation: Unconjugated
Molecular Weight(Calculated): N/A
Molecular Weight(Observed): 48 kDa
