Product Description
PCNA Monoclonal Antibody | E-AB-22001 | Elabscience
Type: Monoclonal Antibody
Synonyms: ATLD2, cb16, Cyclin, DNA polymerase delta auxiliary protein, etID36690.10, fa28e03, fb36g03, HGCN8729, MGC8367, Mutagen-sensitive 209 protein, OTTHUMP00000030189, OTTHUMP00000030190, PCNA, Pcna/cyclin, PCNA, PCNAR, Polymerase delta accessory protein, Proliferating cell nuclear antigen, wu:fa28e03, wu:fb36g03
Application: WB, IHC-p, IF
Reactivity: Human, Mouse, Rat
Host: Mouse
Isotype: IgG
Reserch Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Tags and Cell Markers
Background: This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2.
Concentration: 1 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Synthetic Peptide
Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Purification Method: Protein A purification
Dilution: WB 1:5000-1:10000, IHC 1:100-1:300, IF 1:100-1:300
Clone: Clone:1A1
Conjugation: Unconjugated
Molecular Weight(Calculated): 29 kDa
Molecular Weight(Observed): 29 kDa