Product Description
COPS5 Polyclonal Antibody | E-AB-10415 | Elabscience
Type: Polyclonal Antibody
Synonyms: 38 kDa Mov34 homolog, COP9 (constitutive photomorphogenic) homolog subunit 5, COP9 constitutive photomorphogenic homolog subunit 5, COP9 signalosome complex subunit 5, COP9 signalosome subunit 5, Cop9 subunit 5, COPS 5, cops5, CSN 5, CSN5, CSN5, JAB 1, Jun activation domain binding protein 1, Jun activation domain binding protein, Jun activation domain-binding protein 1, MGC3149, MOV 34, MOV34, MOV34 family, 38-KD member, SGN 5, SGN5, Signalosome subunit 5
Application: WB, IHC, ELISA
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Neuroscience, Signal Transduction
Background: The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors
Concentration: 0.9 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant protein of human COPS5
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: WB 1:1000-1:5000, IHC 1:150-1:500
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 38 kDa
Molecular Weight(Observed): N/A