Product Description
DHCR24 Polyclonal Antibody | E-AB-15380 | Elabscience
Type: Polyclonal Antibody
Synonyms: 24 dehydrocholesterol reductase, 24-dehydrocholesterol reductase, 3 beta hydroxysterol delta 24 reductase, 3-beta-hydroxysterol delta-24-reductase, DCE, Delta(24)-sterol reductase, Desmosterol to cholesterol enzyme, DHC24, Dhcr24, Diminuto dwarf1 homolog, Diminuto/dwarf1 homolog, KIAA0018, Nbla03646, Seladin-1, SELADIN1, Selective AD indicator 1, Selective Alzheimer's Disease Indicator 1
Application: IHC, ELISA
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Cell Biology, Cardiovascular, Metabolism, Neuroscience
Background: This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells.
Concentration: 0.7 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant protein of human DHCR24
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: IHC 1:30-1:150
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): N/A
Molecular Weight(Observed): N/A