Product Description
CTDP1 Polyclonal Antibody | E-AB-17955 | Elabscience
Type: Polyclonal Antibody
Synonyms: CCFDN, CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1, CTD of POLR2A, phosphatase of, subunit 1, CTDP1, CTDP1, EC 3.1.3.16 , RNA polymerase II subunit A C terminal domain phosphatase, RNA polymerase II subunit A C-terminal domain phosphatase, Serine phosphatase FCP1a, TFIIF associating CTD phosphatase , TFIIF-associating CTD phosphatase 1 , TFIIF-associating CTD phosphatase, Transcription factor IIF-associating CTD phosphatase 1
Application: WB, IHC, ELISA
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Reserch Areas: N/A
Background: This gene encodes a protein which interacts with the carboxy-terminus of the RAP74 subunit of transcription initiation factor TFIIF, and functions as a phosphatase that processively dephosphorylates the C-terminus of POLR2A (a subunit of RNA polymerase II), making it available for initiation of gene expression. Mutations in this gene are associated with congenital cataracts, facial dysmorphism and neuropathy syndrome (CCFDN). Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Concentration: 1.56 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Synthetic peptide of human CTDP1
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification Method: Antigen affinity purification
Dilution: WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:5000-1:10000
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 104 kDa
Molecular Weight(Observed): Refer to figures