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Product Description
GRB2 Polyclonal Antibody | E-AB-61066 | Elabscience
Type: Polyclonal Antibody
Synonyms: ASH, EGFRBP-GRB2, Grb3-3, MST084, MSTP084, NCKAP2, GRB2
Application: WB, IHC, IF
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Signal Transduction
Background: The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Concentration: 1 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant fusion protein of human GRB2 (NP_002077.1).
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000 IHC 1:50-1:200 IF 1:10-1:100
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 20 kDa/25 kDa
Molecular Weight(Observed): 33 kDa
