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Product Description
Caspase-7 Polyclonal Antibody | E-AB-60327 | Elabscience
Type: Polyclonal Antibody
Synonyms: CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3, caspase-7, Casp7
Application: WB, IHC, IF
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Cell Biology, Metabolism
Background: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of the encoded protein is cleaved by caspase 3 and 10, is activated upon cell death stimuli and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Concentration: 1 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant fusion protein of human Caspase-7 (NP_001218.1).
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 28 kDa/31 kDa/34 kDa/37 kDa
Molecular Weight(Observed): 37 kDa
