Product Description
DDC Polyclonal Antibody | E-AB-19409 | Elabscience
Type: Polyclonal Antibody
Synonyms: AADC, Aromatic L Amino Acid Decarboxylase, Aromatic-L-amino-acid decarboxylase, DDC, DDC_HUMAN, DOPA decarboxylase (aromatic L-amino acid decarboxylase), DOPA decarboxylase
Application: WB, IHC, ELISA
Reactivity: Human
Host: Rabbit
Isotype: IgG
Reserch Areas: Neuroscience, Cancer, Metabolism
Background: The encoded protein catalyzes the decarboxylation of L-3, 4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
Concentration: 1.5 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Synthetic peptide of human DDC
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification Method: Antigen affinity purification
Dilution: WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 54 kDa
Molecular Weight(Observed): Refer to figures