Product Description
BOD1 Polyclonal Antibody | E-AB-16283 | Elabscience
Type: Polyclonal Antibody
Synonyms: Biorientation defective 1, Biorientation defective protein 1, biorientation of chromosomes in cell division 1, Biorientation of chromosomes in cell division protein 1, BOD1, BOD1, FAM44B, family with sequence similarity 44, member B, Protein FAM44B
Application: IHC, ELISA
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Reserch Areas: Cell biology, Epigenetics and Nuclear Signaling
Background: Bod1, a protein conserved throughout metazoans that associates with a large macromolecular complex and localizes with kinetochores and spindle poles during mitosis.Bod1-depleted cells form syntelic attachments that can oscillate and generate enough force to separate sister kinetochores, suggesting that microtubule-kinetochore interactions were intact. Releasing Bod1-depleted cells from a monastrol block increases the frequency of syntelic attachments and the number of cells displaying biorientation defects.
Concentration: 0.7 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Synthetic peptide of human BOD1
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: IHC 1:50-1:200
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): N/A
Molecular Weight(Observed): N/A