Product Description
C12orf5 Polyclonal Antibody | E-AB-16101 | Elabscience
Type: Polyclonal Antibody
Synonyms: 6-bisphosphatase TIGAR, C12ORF5, chromosome 12 open reading frame 5, FR2BP, Fructose-2, 6-bisphosphatase TIGAR, Fructose-2, 6-bisphosphate 2-phosphatase, Probable fructose 2, 6 bisphosphatase TIGAR, Probable fructose-2, tigar, TIGAR, TP53 induced glycolysis and apoptosis regulator, TP53 induced glycolysis regulatory phosphatase, TP53-induced glycolysis and apoptosis regulator, Transactivated by NS3TP2 protein
Application: IHC, ELISA
Reactivity: Human
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Cell Biology
Background: This gene is regulated as part of the p53 tumor suppressor pathway and encodes a protein with sequence similarity to the bisphosphate domain of the glycolytic enzyme that degrades fructose-2, 6-bisphosphate. The protein functions by blocking glycolysis and directing the pathway into the pentose phosphate shunt. Expression of this protein also protects cells from DNA damaging reactive oxygen species and provides some protection from DNA damage-induced apoptosis. The 12p13.32 region that includes this gene is paralogous to the 11q13.3 region.
Concentration: 0.4 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Synthetic peptide of human C12orf5
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: IHC 1:100-1:300
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): N/A
Molecular Weight(Observed): N/A