Product Description
CSTB Polyclonal Antibody | E-AB-13179 | Elabscience
Type: Polyclonal Antibody
Synonyms: CHROW21, CPI B, CPI-B, CST 6, CST6, CSTB, Cystatin B (stefin B), Cystatin B, Cystatin-B, CYTB, CYTB, EPM1, EPM1A, Liver thiol proteinase inhibitor, PME, Stefin-B, STF B, STFB, ULD
Application: IHC, ELISA
Reactivity: Human
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Cell Biology
Background: The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and kininogens. This gene encodes a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy (EPM1).
Concentration: 0.9 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Synthetic peptide of human CSTB
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: IHC 1:50-1:200
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): N/A
Molecular Weight(Observed): N/A