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Product Description
UBA7 Polyclonal Antibody | E-AB-52436 | Elabscience
Type: Polyclonal Antibody
Synonyms: D8, MGC12713, UBA1, ubiquitin activating enzyme E1 homolog B, UBA1B, UBA7, UBA7, ubiquitin activating enzyme E1, UBA7, Ube 1L, UBE 2, UBE1L, UBE2, Ubiquitin activating enzyme 2, Ubiquitin activating enzyme E1 homolog, Ubiquitin Activating Enzyme E1 Like, Ubiquitin activating enzyme E1 related protein, Ubiquitin-activating enzyme 7, Ubiquitin-activating enzyme E1 homolog, ubiquitin-activating enzyme-2, ubiquitin-like modifier activating enzyme 7, Ubiquitin-like modifier-activating enzyme 7
Application: IHC, ELISA
Reactivity: Human
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling
Background: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme is a retinoid target that triggers promyelocytic leukemia (PML)/retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic leukemia, where it is involved in the conjugation of the ubiquitin-like interferon-stimulated gene 15 protein.
Concentration: 0.6 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Fusion protein of human UBA7
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification Method: Antigen affinity purification
Dilution: IHC 1:30-1:150, ELISA 1:5000-1:10000
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): N/A
Molecular Weight(Observed): N/A
