Product Description
Phospho-YAP1(S127) Polyclonal Antibody | E-AB-68161 | Elabscience
Type: Phosphorylated antibody
Synonyms: COB1, YAP, YAP2, YAP65, YKI, YAP1
Application: WB, IF
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Epigenetics and Nuclear Signaling, Signal Transduction
Background: This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.
Concentration: 1 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: A synthetic phosphorylated peptide around S127 of human YAP1 (NP_001123617.1).
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification Method: Affinity purification
Dilution: WB 1:500-1:1000 IF 1:20-1:100
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 36 kDa/48 kDa/49 kDa/50 kDa/52 kDa/53 kDa/54 kDa
Molecular Weight(Observed): 60 kDa/68 kDa