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Product Description
ARF6 Polyclonal Antibody | E-AB-40035 | Elabscience
Type: Polyclonal Antibody
Synonyms: ADP ribosylation factor 6, ADP ribosylation factor protein 6, ADP-ribosylation factor 6, ARF6, ARF6, DKFZp564M0264, Small GTP binding protein, Small GTPase
Application: WB, IHC
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Signaling transduction
Background: ADP-ribosylation factors (ARFs) are members of the ARF family of GTP-binding proteins of the Ras superfamily, with 20kda protein size. ARFs bind and regulate GTP/GDP cycle by alternating between the active GTP-bound and inactive GDP-bound conformations. ARF family proteins are essential and ubiquitous in eukaryotes. Six highly conserved members of the family have been identified in mammalian cells. They function in vesicular traffic and actin remodelling and other bioprocesses in cells. The ARF6 is one of best identified ARFs It is present at the plasma membrane and to some extent on endosomal membranes where it regulates the flow of trafficking into and out of the cell and the actin cytoskeleton.This antibody can bind ARFs for the close sequences.
Concentration: 2 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant Human ADP-ribosylation factor 6 protein
Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Purification Method: Affinity purification
Dilution: WB 1:500-1:1000, IHC 1:50-1:100
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 20 kDa
Molecular Weight(Observed): N/A
