Product Description
CK-7 Polyclonal Antibody | E-AB-40292 | Elabscience
Type: Polyclonal Antibody
Synonyms: CK 7, Cytokeratin 7, D15Wsu77e, K2C7, K7, Keratin 7, Keratin type II cytoskeletal 7, Krt2-7, MGC11625, Sarcolectin, Type II mesothelial keratin K7
Application: WB, IHC
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Signal Transduction
Background: Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells, which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins, including K9–K23, and the hair keratins Ha1–Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1–K8, and the hair keratins, Hb1–Hb6. KRT7, also named as cytokeratin 7, is one member of type II basic cytokeratin. It is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels, and their neoplasms. KRT7 is marker of epithelial tissues, but not present in carcinomas of stratified squamous cell origin.This antibody is specifically against KRT7.
Concentration: 0.85 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant Mouse Keratin, type II cytoskeletal 7 protein
Buffer: PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.
Purification Method: Antigen Affinity Purification
Dilution: WB 1:500-1:2000 IHC 1:100-1:200
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 51 kDa
Molecular Weight(Observed): 51 kDa