Product Description
PCNA Polyclonal Antibody | E-AB-40056 | Elabscience
Type: Polyclonal Antibody
Synonyms: ATLD2, cb16, Cyclin, DNA polymerase delta auxiliary protein, etID36690.10, fa28e03, fb36g03, HGCN8729, MGC8367, Mutagen-sensitive 209 protein, OTTHUMP00000030189, OTTHUMP00000030190, PCNA, Pcna/cyclin, PCNA, PCNAR, Polymerase delta accessory protein, Proliferating cell nuclear antigen, wu:fa28e03, wu:fb36g03
Application: WB, IHC
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Tags and Cell Markers
Background: This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2.
Concentration: 2 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant human Proliferating cell nuclear antigen protein
Buffer: PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.
Purification Method: Affinity purification
Dilution: WB 1:500-1:1000, IHC 1:50-1:100
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 29 kDa
Molecular Weight(Observed): 34 kDa