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Product Description
14-3-3 epsilon Polyclonal Antibody | E-AB-12585 | Elabscience
Type: Polyclonal Antibody
Synonyms: 14 3 3 E, 14 3 3 epsilon, 14 3 3E, 14-3-3 protein epsilon, 14-3-3E, 1433E, Epididymis luminal protein 2, FLJ45465, FLJ53559, HEL2, KCIP 1, KCIP1, MDCR, MDS, Mitochondrial import stimulation factor L subunit, Protein kinase C inhibitor protein1, Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein, epsilon, Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein, epsilon polypeptide, Tyrosine 3/tryptophan 5 monooxygenase activation protein epsilon polypeptide, YWHAE
Application: WB, IHC, ELISA
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Neuroscience, Signal Transduction, Stem Cells
Background: This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene.
Concentration: 0.8 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Synthetic peptide of human YWHAE
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: WB 1:1000-1:5000, IHC 1:50-1:200
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 29 kDa
Molecular Weight(Observed): N/A
