Product Description
BMI1 Polyclonal Antibody | E-AB-40381 | Elabscience
Type: Polyclonal Antibody
Synonyms: B lymphoma Mo MLV insertion region (mouse), B lymphoma Mo MLV insertion region 1 homolog, Bmi 1, BMI1, BMI1 polycomb ring finger oncogene, BMI1, Flvi 2/bmi 1, FLVI2/BMI1, MGC12685, Murine leukemia viral (bmi 1) oncogene homolog, Oncogene BMI 1, PCGF 4, PCGF4, Polycomb complex protein BMI 1, Polycomb complex protein BMI-1, Polycomb group protein Bmi1, Polycomb group ring finger 4, Polycomb group RING finger protein 4, RING finger protein 51, RNF 51, RNF51
Application: WB
Reactivity: Mouse
Host: Rabbit
Isotype: IgG
Reserch Areas: Cell Biology, Epigenetics and Nuclear Signaling, Stem Cells, Cancer
Background: BMI- 1 is one of polycomb group genes, which together with Ring1 strongly enhances the E3 ubiquitin ligase activity of the Ring2 catalytic subunit. Bmi1 plays an important role in the regulation of cell proliferation and senescence through repression of the p16Ink4a and p19Arf genes and is required for maintenance of adult hematopoietic and neural stem cells. The antibody reacts with the 37kd BMI1 protein.
Concentration: 0.18 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant Mouse Polycomb complex protein BMI-1 protein
Buffer: PBS with 0.05% Proclin300, 50% glycerol, pH7.3
Purification Method: Antigen Affinity Purification
Dilution: WB 1:500-1:1000
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 36 kDa
Molecular Weight(Observed): 36 kDa