Product Description
COL2A1 Monoclonal Antibody | E-AB-70295 | Elabscience
Type: Monoclonal Antibody
Synonyms: Alpha 1 type II collagen, Alpha-1 type II collagen, AOM, Cartilage collagen, Chondrocalcin, CO2A1, COL11A3, Col2a1, Collagen II alpha 1 polypeptide, SEDC
Application: IHC
Reactivity: Mouse, Rat
Host: Mouse
Isotype: IgG
Reserch Areas: Cancer, Signal Transduction, Stem Cells
Background: This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene.
Concentration: 2.6 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant protein corresponding to Mouse collagen II
Buffer: PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4
Purification Method: Affinity purification
Dilution: IHC 1:300-1:1000
Clone: 2F12D3
Conjugation: Unconjugated
Molecular Weight(Calculated): N/A
Molecular Weight(Observed): N/A