Product Description
ATPIF1 Polyclonal Antibody | E-AB-10676 | Elabscience
Type: Polyclonal Antibody
Synonyms: ATIF1, ATP synthase inhibitor protein, ATPase inhibitor, ATPase inhibitor mitochondrial, ATPase inhibitor protein, ATPase inhibitory factor 1, ATPI, ATPIF 1, Atpif1, ATPIP, IF(1), IF1, Inhibitor of F(1)F(o)-ATPase, IP, MGC1167, MGC8898, mitochondrial
Application: WB, IHC, ELISA
Reactivity: Human
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Metabolism, Signal Transduction, Tags and Cell Markers
Background: ATPase inhibitor, mitochondrialis anenzymethat in humans is encoded by theATPIF1gene. This gene encodes a mitochondrial ATPase inhibitor. Alternative splicing occurs at this locus and three transcript variants encoding distinct isoforms have been identified. It prevents ATPase from switching to ATP hydrolysis during collapse of the electrochemical gradient, for example during oxygen deprivation ATP synthase inhibitor forms a one to one complex with the F1 ATPase, possibly by binding at the alpha-beta interface. It is thought to inhibit ATP synthesis by preventing the release of ATP. The inhibitor has two oligomeric states, dimer (the active state) and tetramer.
Concentration: 0.2 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant protein of human ATPIF1
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: WB 1:1000-1:5000, IHC 1:50-1:200
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 12 kDa
Molecular Weight(Observed): N/A