Product Description
PRAME Polyclonal Antibody | E-AB-52200 | Elabscience
Type: Polyclonal Antibody
Synonyms: 4930534P07Rik, Cancer/testis antigen 130, CT130, MAPE, Melanoma antigen preferentially expressed in tumors, OIP 4, OIP-4, OIP4 , OPA interacting protein 4, Opa interacting protein OIP4, OPA-interacting protein 4, PRAME, PRAME, Preferentially expressed antigen in melanoma , Preferentially expressed antigen of melanoma, RP23-250F8.3
Application: IHC, ELISA
Reactivity: Human
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Epigenetics and Nuclear Signaling, Tags & Cell Markers
Background: This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants.
Concentration: 1.1 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Fusion protein of human PRAME
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification Method: Antigen affinity purification
Dilution: IHC 1:40-1:250, ELISA 1:5000-1:10000
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): N/A
Molecular Weight(Observed): N/A