Product Description
CMKLR1 Polyclonal Antibody | E-AB-66470 | Elabscience
Type: Polyclonal Antibody
Synonyms: CMKLR1, CHEMERINR, ChemR23, DEZ, RVER1
Application: WB
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Cell Biology, Signal Transduction
Background: Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 induces activation of intracellular signaling molecules, such as SKY, MAPK1/3 (ERK1/2), MAPK14/P38MAPK and PI3K leading to multifunctional effects, like, reduction of immune responses, enhancing of adipogenesis and angionesis. Resolvin E1 down-regulates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2) and NF-kappa-B. Positively regulates adipogenesis and adipocyte metabolism. Acts as a coreceptor for several SIV strains (SIVMAC316, SIVMAC239, SIVMACL7E-FR and SIVSM62A), as well as a primary HIV-1 strain (92UG024-2).
Concentration: 1 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: A synthetic peptide of human CMKLR1 (NP_001135815.1).
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 42 kDa
Molecular Weight(Observed): 45 kDa