Product Description
A potent, brain-penetrant, and water-soluble poly(ADP-ribose) polymerase (PARP) inhibitor. IC₅₀ values are 0.20 and 0.24 µM for PARP-1 and PARP-2 respectively. Neuroprotective in vitro and in vivo.
DR2313 is a potent, brain-penetrant, and water-soluble poly(ADP-ribose) polymerase (PARP) inhibitor. IC₅₀ values are 0.20 and 0.24 µM for PARP-1 and PARP-2 respectively. Neuroprotective in vitro and in vivo.
Biovision | 1771 | DR2313 DataSheet
Alternate Name/Synonyms: 1,5,7,8-Tetrahydro-2-methyl-4H-thiopyrano[4,3-d]pyrimid in-4-one
Appearance: Off-white to white solid
Formulation: N/A
CAS Number: 284028-90-6
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₈H₁₀N₂OS
Molecular Weight: 182.24
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: H₂O (40 mM)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A PARP inhibitor
MDL Number: MFCD08703132
PubChem CID: 10219702
SMILES: CC1=NC(=O)C2=C(N1)CCSC2
InChi: InChI=1S/C8H10N2OS/c1-5-9-7-2-3-12-4-6(7)8(11)10-5/h2-4H2,1H3,(H,9,10,11)
InChi Key: HRYKZAKEAVZGJD-UHFFFAOYSA-N