Product Description
Anti- ARAP3 Antibody | FNab00523 | FineTest
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Phosphatidylinositol 3, 4, 5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. Is activated by phosphatidylinositol 3, 4, 5-trisphosphate (PtdIns (3, 4, 5) P3) binding. Can be activated by phosphatidylinositol 3, 4-bisphosphate (PtdIns (3, 4, 5) P2) binding, albeit with lower efficiency. Acts on ARF6, RAC1, RHOA and CDC42. Plays a role in the internalization of anthrax toxin.
Immunogen: ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
synonyms: CENTD3
Molecular weight (observed) : 45 kDa
Reactivity Species: Human
Tested Application: ELISA, WB, IHC
Recomended Dillution : IHC: 1:20-1:200
Research Area: Signal Transduction