Product Description
Anti- C4 (alpha chain) Antibody | FNab01111 | FineTest
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Complement C4, a component of the classical complement pathway, has an important role in innate immune function. C4 protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains (molecular wights 95, 78, and 31 kDa) prior to secretion. The alpha chain is cleaved to release C4 anaphylatoxin, an antimicrobial peptide and a mediator of local inflammation. This antibody can recognize C4 precursor, C4 alpha chain, C4b, and C4d.
Immunogen: complement component 4A (Rodgers blood group)
synonyms: N/A
Molecular weight (observed) : 95 kDa
Reactivity Species: Human
Tested Application: ELISA, WB, IF
Recomended Dillution : WB: 1:1000-1:6000; IHC: 1:50-1:500
Research Area: Epigenetics, Signal Transduction, Metabolism, Cardiovascular, Immunology, Developmental biology, Neuroscience