Product Description
Anti- MLKL Antibody | FNab05217 | FineTest
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.
Immunogen: mixed lineage kinase domain-like
synonyms: N/A
Molecular weight (observed) : 54 kDa
Reactivity Species: Human
Tested Application: ELISA, WB, IF, IHC
Recomended Dillution : WB: 1:500-1:2000
Research Area: Metabolism