Product Description
Anti- BAK Antibody | FNab00796 | FineTest
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.
Immunogen: BCL2-antagonist/killer 1
synonyms: Apoptosis regulator BAK, BAK, BAK LIKE, BAK1, CDN1
Molecular weight (observed) : 26 kDa
Reactivity Species: Human, Mouse, Rat
Tested Application: ELISA, WB, IF
Recomended Dillution : WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
Research Area: Neuroscience, Cancer, Immunology, Cardiovascular