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Product Description
Anti- BAX Antibody | FNab00809 | FineTest
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene.
Immunogen: BCL2-associated X protein
synonyms: BCL2L4, Apoptosis regulator BAX, BAX
Molecular weight (observed) : 21 kDa
Reactivity Species: Human, Mouse, Rat
Tested Application: ELISA, IP
Recomended Dillution : WB: 1:500 - 1:2000; IHC: 1:50 - 1:100; IF: 1:50 - 1:200
Research Area: Neuroscience, Cancer, Developmental biology
