Product Description
Anti- TIA1 Antibody | FNab08685 | FineTest
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly (A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms of this gene product has been described in the literature.
Immunogen: TIA1 cytotoxic granule-associated RNA binding protein
synonyms: N/A
Molecular weight (observed) : 54 kDa
Reactivity Species: Human, Mouse, Rat
Tested Application: ELISA, IHC
Recomended Dillution : WB: 1:500 - 1:2000; IHC: 1:50 - 1:100; IF: 1:20 - 1:100
Research Area: Cancer, Immunology, Metabolism