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Product Description
Anti- TMEM173 Antibody | FNab08759 | FineTest
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.
Immunogen: transmembrane protein 173
synonyms: ERIS, hMITA, hSTING, MITA, MPYS, NET23, SAVI, STING
Molecular weight (observed) : 39 kDa
Reactivity Species: Human, Mouse
Tested Application: ELISA, IHC
Recomended Dillution : WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
Research Area: Cancer, Immunology, Epigenetics
