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Product Description
Anti- UCHL1/PGP9.5 Antibody | FNab09218 | FineTest
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: UCHL1 (Ubiquitin carboxyl-terminal hydrolase isozyme L1) is a member of a gene family whose products hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer. Expression of UCHL1 is highly specific to neurons and to cells of the diffuse neuroendocrine system and their tumors. It is present in all neurons (PMID: 6343558) . This protein is present in brain at concentrations at least 50 times greater than in other organs and is a major protein component of neuronal cytoplasm (PMID:7217993) . And UCHL1 is a Parkinson's disease susceptibility gene (PMID:15048890) .
Immunogen: ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
synonyms: Neuron cytoplasmic protein 9.5, PARK5, PGP 9.5, PGP9.5, Ubiquitin thioesterase L1, Uch L1, UCHL1
Molecular weight (observed) : 26 kDa
Reactivity Species: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC, IF
Recomended Dillution : WB: 1:500-1:5000; IHC：1:100-1:500; IP: 1:1000-1:5000
Research Area: Neuroscience, Cancer, Metabolism, Epigenetics
