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Product Description
Anti- UACA Antibody | FNab09140 | FineTest
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation. Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1 (By similarity) . Modulates isoactin dynamics to regulate the morphological alterations required for cell growth and motility. Interaction with ARF6 may modulate cell shape and motility after injury. May be involved in multiple neurite formation (By similarity) .
Immunogen: uveal autoantigen with coiled-coil domains and ankyrin repeats
synonyms: FLJ10128, KIAA1561, NUCLING, UACA
Molecular weight (observed) : 163 kDa
Reactivity Species: Human, Mouse
Tested Application: ELISA, WB, IHC
Recomended Dillution : WB: 1:1000-1:10000; IF: 1:20-1:200
Research Area: Immunology, Cell Division and Proliferation
![UACA Antibody [UACA/1222]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/575296/811831/porsci_lo__79508.1648973713__63771.1649091885.png?c=2 "UACA Antibody [UACA/1222]")
