Product Description
Anti- BANP Antibody | FNab00799 | FineTest
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Controls V (D) J recombination during T-cell development by repressing T-cell receptor (TCR) beta enhancer function. Binds to scaffold/matrix attachment region beta (S/MARbeta), an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Represses cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 'Ser-15' phosphorylation and nuclear accumulation, which causes cell cycle arrest (By similarity) .
Immunogen: BTG3 associated nuclear protein
synonyms: BANP, BEND1, Protein BANP, SMAR1, SMARBP1
Molecular weight (observed) : 56kd
Reactivity Species: Human, Mouse, Rat
Tested Application: ELISA, IHC, WB
Recomended Dillution : WB: 1:500-1:1000; IHC: 1:50-1:500
Research Area: Metabolism, Developmental biology