Product Description
Anti- Histone-H3 Antibody | FNab03890 | FineTest
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: HIST2H3A, histone cluster 2, H3a.It is the core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. HIST2H3A is Expressed during S phase, then expression strongly decreases as cell division slows down during the process of differentiation.
Immunogen: histone cluster 2, H3a
synonyms: H3/n, H3/o, H3F2, H3FM, HIST2H3A, HIST2H3C, HIST2H3D, histone cluster 2, H3a, Histone H3, Histone H3.2, Histone H3/m, Histone H3/o
Molecular weight (observed) : 15-17 kDa
Reactivity Species: Human, Mouse, Rat
Tested Application: ELISA, IHC, WB, IP
Recomended Dillution : WB: 1:500-1:5000; IHC: 1:50-1:200; IF: 1:20-1:200
Research Area: Epigenetics, Metabolism