Product Description
Anti- TRIM37 Antibody | FNab08982 | FineTest
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: E3 ubiquitin-protein ligase required to prevent centriole reduplication (PubMed:15885686, PubMed:23769972) . Probably acts by ubiquitinating positive regulators of centriole reduplication (PubMed:23769972) . Mediates monoubiquitination of 'Lys-119' of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression: associates with some Polycomb group (PcG) multiprotein PRC2-like complex and mediates repression of target genes (PubMed:25470042) . Has anti-HIV activity (PubMed:24317724) .
Immunogen: tripartite motif-containing 37
synonyms: TRIM37, POB1, TEF3, MUL, tripartite motif containing 37
Molecular weight (observed) : 100kDa, 130kDa
Reactivity Species: Human, Mouse, Rat
Tested Application: ELISA, WB
Recomended Dillution : WB: 1:500-1:5000
Research Area: Epigenetics, Metabolism