Product Description
Anti- BMI1 Antibody | FNab00914 | FineTest
Form: liquid
Purification: Protein A+G purification
Purity: ≥95% as determined by SDS-PAGE
Host: Mouse
Clonality: monoclonal
Clone ID: 8D5
Isotype: IgG1
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
Immunogen: BMI1 polycomb ring finger oncogene
synonyms: BMI1, PCGF4, Polycomb complex protein BMI 1, RING finger protein 51, RNF51
Molecular weight (observed) : 37 kDa
Reactivity Species: Human, Mouse
Tested Application: ELISA, WB, IHC, IF, IP
Recomended Dillution : WB: 1:500-1:2000; IP: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:10-1:100
Research Area: Epigenetics, Metabolism, Cancer, Developmental biology, Stem Cells, Cell Division and Proliferation