Euro
USD
British Pound
NULL
Product Description
Anti- IL1 Beta Antibody | FNab04210 | FineTest
Form: liquid
Purification: Protein G purified
Purity: ≥95% as determined by SDS-PAGE
Host: Mouse
Clonality: monoclonal
Clone ID: 9G5
Isotype: IgG1
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE) . This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.
Immunogen: interleukin 1, beta
synonyms: IL1 beta, Catabolin, IL 1, IL 1 beta, IL1 BETA, IL1B, IL1beta, IL1F2, IL-1β, Interleukin 1 beta, interleukin 1, beta
Molecular weight (observed) : 35kDa
Reactivity Species: Human
Tested Application: ELISA, IHC, WB
Recomended Dillution : WB: 1:1000-1:4000; IHC: 1:50-1:500
Research Area: Neuroscience, Immunology, Cardiovascular, Signal Transduction
