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Product Description
Anti- ITM2C Antibody | FNab04419 | FineTest
Form: liquid
Purification: Protein A+G purification
Purity: ≥95% as determined by SDS-PAGE
Host: Mouse
Clonality: monoclonal
Clone ID: 5D9
Isotype: IgG2a
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Negative regulator of beta amyloid peptide production. May inhibit the processing of APP by blocking its access to alpha-and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation (By similarity) .
Immunogen: integral membrane protein 2C
synonyms: BRI3
Molecular weight (observed) : 35 kDa
Reactivity Species: Human
Tested Application: ELISA, WB, IHC
Recomended Dillution : WB: 1:500-1:1000; IF: 1:20-1:200
Research Area: Neuroscience
