Product Description
Anti- N-cadherin Antibody | FNab05571 | FineTest
Form: liquid
Purification: Protein A+G purification
Purity: ≥95% as determined by SDS-PAGE
Host: Mouse
Clonality: monoclonal
Clone ID: 1G1
Isotype: IgG2a
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density (By similarity) .
Immunogen: cadherin 2, type 1, N-cadherin (neuronal)
synonyms: Cadherin 2, CD325, CDH2, CDHN, CDw325, N cadherin, NCAD, N-cadherin, Neural cadherin
Molecular weight (observed) : 130 kDa
Reactivity Species: Human, Mouse, Rat
Tested Application: ELISA, IP, WB, IHC, FC
Recomended Dillution : WB: 1:1000-1:10000; IHC: 1:20-1:200
Research Area: Signal Transduction, Cardiovascular, Immunology, Neuroscience, Stem Cells