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Product Description
Anti- NUMB Antibody | FNab05916 | FineTest
Form: liquid
Purification: Protein A+G purification
Purity: ≥95% as determined by SDS-PAGE
Host: Mouse
Clonality: monoclonal
Clone ID: 0E11
Isotype: IgG2a
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of neurogenesis. Also involved postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. May also mediate local repair of brain ventricular wall damage.
Immunogen: numb homolog (Drosophila)
synonyms: N/A
Molecular weight (observed) : 68 kDa
Reactivity Species: Human, Mouse
Tested Application: ELISA, WB
Recomended Dillution : WB: 1:200-1:1000; IHC: 1:50-1:500; IF: 1:20-1:200
Research Area: Signal Transduction, Cardiovascular, Immunology, Developmental biology, Neuroscience, Stem Cells
