Product Description
Anti- P62/SQSTM1 Antibody | FNab09853 | FineTest
Form: liquid
Purification: protein A+G purified
Purity: ≥95% as determined by SDS-PAGE
Host: mouse
Clonality: monoclonal
Clone ID: 5H3
Isotype: IgG2a
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.
Immunogen: sequestosome 1
synonyms: P62, sequestosome 1, SQSTM1, Ubiquitin binding protein p62
Molecular weight (observed) : 62 kDa
Reactivity Species: Human, Mouse
Tested Application: ELISA, WB, IHC, IF, IP
Recomended Dillution : WB: 1:1000 - 1:4000; IHC: 1:50 - 1:500; IF: 1:20 - 1:200
Research Area: Neuroscience, Cardiovascular, Metabolism, Signal Transduction