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Product Description
Anti- PARP1 Antibody | FNab09939 | FineTest
Form: liquid
Purification: protein A+G purified
Purity: ≥95% as determined by SDS-PAGE
Host: Mouse
Clonality: monoclonal
Clone ID: 4A9
Isotype: IgG1
Storage: 0.01MPBS pH 7.4, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: PARP1 (poly (ADP-ribose) polymerase 1) is a nuclear enzyme catalyzing the poly (ADP-ribosyl) ation of many key proteins in vivo. The normal function of PARP1 is the routine repair of DNA damage. Activated by DNA strand breaks, the PARP1 is cleaved into an 85 to 89-kDa COOH-terminal fragment and a 24-kDa NH2-terminal peptide by caspases during the apoptotic process. The appearance of PARP fragments is commonly considered as an important biomarker of apoptosis.
Immunogen: poly (ADP-ribose) polymerase 1
synonyms: ADPRT, ADPRT 1, ADPRT1, pADPRT 1, PARP, PARP 1, PARP1, poly (ADP ribose) polymerase 1, Poly [ADP ribose] polymerase 1, Poly[ADP ribose] synthase 1, PPOL
Molecular weight (observed) : 115 kDa, 89 kDa
Reactivity Species: Human, Mouse, Rat
Tested Application: ELISA, IHC, WB, IF
Recomended Dillution : WB: 1:5000 - 1:30000; IHC: 1:100 - 1:1000; IF: 1:50 - 1:500
Research Area: Metabolism
