Product Description
Anti- SOX2 Antibody | FNab10148 | FineTest
Form: liquid
Purification: protein A+G purified
Purity: ≥95% as determined by SDS-PAGE
Host: Mouse
Clonality: monoclonal
Clone ID: 1B5
Isotype: IgG1
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity) . Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity) . Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity) .
Immunogen: SRY (sex determining region Y) -box 2
synonyms: ANOP3, MCOPS3, SOX2, Transcription factor SOX 2
Molecular weight (observed) : 34kd
Reactivity Species: Human, Mouse
Tested Application: WB
Recomended Dillution : WB: 1:500-1:2000; IHC: 1:50-1:200
Research Area: Neuroscience, Stem Cells, Metabolism, Epigenetics