Product Description
Anti- STIM1 Antibody | FNab08321 | FineTest
Form: liquid
Purification: Protein A+G purification
Purity: ≥95% as determined by SDS-PAGE
Host: Mouse
Clonality: monoclonal
Clone ID: 4G6
Isotype: IgG2a
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Plays a role in mediating store-operated Ca (2+) entry (SOCE), a Ca (2+) influx following depletion of intracellular Ca (2+) stores (By similarity) . Acts as Ca (2+) sensor in the endoplasmic reticulum via its EF-hand domain. Upon Ca (2+) depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca (2+) release-activated Ca (2+) (CRAC) channel subunit ORAI1 (PubMed:16208375) . Involved in enamel formation (By similarity) . Activated following interaction with TMEM110/STIMATE, leading to promote STIM1 conformational switch (By similarity) .
Immunogen: stromal interaction molecule 1
synonyms: D11S4896E, GOK, STIM1, stromal interaction molecule 1
Molecular weight (observed) : 77kd
Reactivity Species: Human, Mouse, Rat
Tested Application: ELISA, WB, IP, IHC, IF, FC
Recomended Dillution : WB: 1:200-1:2000 IHC: 1:50-1:500
Research Area: Neuroscience, Immunology