Product Description
Anti- TLR4 Antibody | FNab09837 | FineTest
Form: liquid
Purification: Protein A+G purification
Purity: ≥95% as determined by SDS-PAGE
Host: Mouse
Clonality: monoclonal
Clone ID: 3E7
Isotype: IgG2b
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: TLR4, also named as CD284, belongs to the Toll-like receptor family. TLR4 cooperates with LY96 and CD14 to mediates the innate immune response to bacterial lipopolysaccharide (LPS) . TLR4 acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Three alternatively spliced transcript variants that encode different protein isoforms have been described.
Immunogen: toll-like receptor 4
synonyms: ARMD10, CD284, hToll, TLR4, TOLL, toll like receptor 4
Molecular weight (observed) : 100 kDa
Reactivity Species: Human, Mouse, Rat
Tested Application: ELISA, WB
Recomended Dillution : WB: 1:1000-1:8000; IHC: 1:50-1:500
Research Area: Neuroscience, Immunology, Signal Transduction, Developmental biology