Product Description
Anti- P Glycoprotein Antibody | FNab09805 | FineTest
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: ABCB1 (also known as P-gp/ P-glycoprotein, MDR1/multidrug-resistance 1) is a plasma membrane protein first discovered in multidrug resistant tumor cells. ABCB1 can extrude a large number of medically relevant compounds from cells and causes drug resistance. ABCB1 is expressed in a variety of human cancers as well as normal tissues including brain, and placenta. Overexpression of ABCB1 correlates with a negative prognosis in several types of cancer.
Immunogen: ABCB1
synonyms: ABCB1, CD243, GP170, MDR1, Multidrug resistance protein 1, P glycoprotein 1
Molecular weight (observed) : 142 kDa
Reactivity Species: Human, Mouse
Tested Application: ELISA, IHC, WB
Recomended Dillution : WB: 1:200-1:1000; IP: 1:200-1:1000; IHC: 1:50-1:500
Research Area: Neuroscience, Immunology, Metabolism