Product Description
Anti- YWHAB Antibody | FNab09575 | FineTest
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by SRPK2. Negative regulator of signaling cascades that mediate activatation of MAP kinases via AKAP13.
Immunogen: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
synonyms: 14 3 3, 14 3 3 alpha, 14 3 3 protein beta/alpha, YWHAB
Molecular weight (observed) : 28 kDa
Reactivity Species: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC
Recomended Dillution : IHC: 1:20-1:200
Research Area: Neuroscience, Signal Transduction, Metabolism